New Study Confirms ARESTIN® + SRP More Effective Than SRP Alone in Eliminating Periodontal Pathogens

New Study Confirms ARESTIN® + SRP More Effective Than SRP Alone in Eliminating Periodontal Pathogens

ARESTIN® shown to significantly reduce bacteria responsible for Periodontal Disease.

Warminster, PA (PRWEB) March 11, 2006

A new study highlighting the antimicrobial effectiveness of ARESTIN® (minocycline hydrochloride) 1 mg Microspheres in the treatment of periodontal disease will be presented at the first joint annual session of the American Dental Education Association (ADEA) and the American Association for Dental Research (AADR), March 8 -11, 2006 in Orlando, Florida.

The study reveals a significant reduction in Red Complex Bacteria among patients with periodontal disease who were treated with ARESTIN® plus scaling and root planing (SRP) compared with patients who were treated with SRP alone. In addition, the study shows that ARESTIN® + SRP is more effective than SRP alone in:

 Reducing periodontal pocket depth  Reducing bleeding on probing  Increasing clinical attachment level  Reducing periodontal pocket depth and bleeding on probing in smokers

Red Complex Bacteria (RCB) includes three pathogens associated with microbial infection in people with periodontal disease: Porphyromonas gingivalis, Tannerella forsythensis and Treponema denticola. More than 50 million adults across many demographic categories are affected by periodontal disease.1 Advanced periodontal disease is marked by tender, swollen and painful gums that bleed easily. After initial development of the disease, the gums may ulcerate and then become necrotic, leading to tooth loss.2

Scaling and Root Planing (SRP) is the removal of hard and soft deposits from the root surfaces of the teeth using mechanical or ultrasonic devices, thereby permitting healing and potential reduction in depth of the periodontal pocket, which is the space that forms at the gum line around teeth. The study, to be presented at the joint ADEA and AADR annual session, shows that, in comparison to SRP alone, a statistically significant reduction in the numbers of infection-causing Red Complex Bacteria is achieved when ARESTIN® is administered as an adjunct to SRP. The ARESTIN® Microspheres are placed into the periodontal pockets, to which they adhere and deliver therapeutic drug concentrations for up to 14 days after administration.3

“We know that scaling and root planing is effective for gross removal of bacterial plaque and calculus in patients with periodontal disease,” states Dr. J. Max Goodson, Senior Member of the Staff and Director of Clinical Research at The Forsyth Institute. “These studies, however, are important because they demonstrate that when SRP was followed by administration of ARESTIN®, there was a significant added reduction in bacteria that are thought to cause periodontal disease. Hence, the inclusion of ARESTIN® with mechanical treatment more effectively controlled these bacteria and created a measurably better clinical outcome.”

About the Study:

The study, titled “Effect of Adjunctive Treatment with ARESTIN® on the Subgingival Microflora in Patients with Moderate to Advanced Periodontitis,” is a phase IV, multicenter, single-blind, randomized, parallel-group study of 127 patients. The study will be presented by its authors as follows:

 Lead Investigator Dr. J. Max Goodson, Senior Member of the Department of Periodontology at The Forsyth Institute, will discuss the “Antimicrobial Efficacy of ARESTIN® in Periodontitis Therapy.” This discussion will cover data from this study on the use of ARESTIN® plus SRP and its ability to reduce numbers and proportions of Red Complex Bacteria to a significantly greater degree than SRP alone. This data indicates that the antimicrobial effect of ARESTIN® plus SRP exceeded that of SRP alone.

 Principal Investigator Dr. John C. Gunsolley, Assistant Professor, Department of Periodontics at the University of Maryland Dental School, will discuss, “Association between the Antimicrobial and Clinical Finding with ARESTIN®” when used as an adjunct to SRP.

 Dr. Paul S. Bland, Assistant Professor at the University of Tennessee Health Science Center, also a Principal Investigator for this study, will discuss “Clinical Efficacy and Safety with ARESTIN® in Patients with Periodontitis.” The objective of his presentation is to discuss ARESTIN® plus SRP’s efficacy vs. SRP alone in reducing periodontal pocket depths, decreasing the number of periodontal pockets ≥5mm, decreasing Bleeding on Probing (a key clinical indicator of disease presence) and increasing the clinical attachment level, or CAL. He will also confirm the therapeutic safety of ARESTIN®.

 Dr. Sara G. Grossi, Senior Research Scientist at East Carolina University, and Principal Investigator for this study, is presenting a “Subset Analysis by Smoking Status with ARESTIN® in Periodontitis Therapy.” The objective of this presentation is to analyze the antimicrobial and clinical effects of ARESTIN® as an adjunct to SRP in relation to smoking status. ARESTIN® plus SRP significantly reduced RCB numbers in current smokers. In addition, ARESTIN plus SRP resulted in greater periodontal pocket depth reduction and decreased bleeding on probing compared with SRP alone regardless of smoking status.

The important findings and results of each of these clinical studies will be presented in their entirety at the first joint annual session of the American Dental Education Association (ADEA) and the American Association for Dental Research (AADR), March 8 -11, 2006 in Orlando, Florida. For presentation times and room/booth locations, contact John Lenart, Senior Product Manager, OraPharma at Jlenart@cpcus. jnj. com.

About OraPharma, Inc.

OraPharma, Inc., is a specialty pharmaceutical company that discovers, develops and commercializes therapeutics for oral health. OraPharma is dedicated to the dental community, specifically the periodontal space, with its lead product, ARESTIN ® (minocycline hydrochloride) 1 mg Microspheres.

ARESTIN® is indicated as an adjunct to scaling and root planing procedures for reduction of pocket depth in patients with adult periodontitis. ARESTIN® may be used as part of a periodontal maintenance program which includes good oral hygiene, scaling and root planing.

The most common treatment-emergent adverse events were headache (9.0%), infection (7.6%), flu syndrome (5.0%), and pain (4.3%). These occurred at a similar rate to SRP and SRP + placebo. For additional product information, visit www. arestin. com.

In addition to ARESTIN®, OraPharma also distributes Oraqix® (lidocaine and prilocaine periodontal gel) 2.5% / 2.5%, a new sub-gingival local anesthetic periodontal gel indicated for adults who require localized anesthesia in periodontal pockets during scaling and/or root planing, and is manufactured by Dentsply Pharmaceuticals. For more information, visit www. orapharma. com.

References:

1. Albander JM, Brunelle JA, Kingman A. Destructive Periodontal Disease in Adults 30 Years of Age and Older in the United States, 1984-1994. J Periodontal 1999; 70:13-29. Accessed on February 27, 2006 at: http://www. perio. org/consumer/disease_facts. htm (http://www. perio. org/consumer/disease_facts. htm).

2. American Academy of Periodontology. Periodontal (Gum) Diseases. Accessed on February 27, 2006 at: http://www. perio. org/consumer/2a. html (http://www. perio. org/consumer/2a. html).

3. ARESTIN® Prescribing Information. OraPharma, Inc. Warminster, PA, 2005.

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One Health Commission Formed to Promote Collaboration Across Human, Animal, and Environmental Health Sciences

One Health Commission Formed to Promote Collaboration Across Human, Animal, and Environmental Health Sciences

One Health Commission Formed to Promote Collaboration Across Human, Animal, and Environmental Health Sciences

Washington, DC (PRWEB) August 27, 2009

A new national commission, the One Health Commission, has been established to spotlight the connections between human, animal, and environmental health, as well as the benefits of proactive and collaborative approaches toward better health for all.

The formation of the Commission comes at a time of heightened concern by policy makers and public health officials about the potential spread of newly emerging infectious diseases such as H1N1 Influenza, as well increasing threats posed by other emerging zoonotic diseases, food - and water-borne diseases, and environmental change.

The Commission represents a call for greater cooperation across multiple disciplines at the local, national, and global level to achieve optimal health for people, domestic animals, wildlife, and the environment. To that end, the Commission's goals include developing an integrated public health strategy; raising awareness of the value of "one health" nationally and internationally; developing an interdisciplinary research agenda for the "one health" movement; and implementing "one health" principles into demonstration research and educational projects.

According to Dr. Ronald Atlas, who was elected chair of the Board of Directors and who represents the American Society for Microbiology, "The One Health Commission brings together eight of the major professional organizations involved in health research, education, and practice.

Given that 75% of newly emerging human infectious diseases originate within wildlife and domesticated animals, and that global warming and other environmental changes are likely to have significant health impacts, it is essential that the medical, veterinary, and public health sectors join forces."

Other members of the Board of Directors are Dr. Albert Osbahr III, vice-chair, representing the American Medical Association; Dr. Michael Cates, secretary-treasurer, representing the American Veterinary Medical Association; Elizabeth Bishop, representing the Association of Academic Health Centers; Dr. John Fischer, representing the Association of Fish and Wildlife Agencies; Dr. James Fox, representing the Association of American Veterinary Medical Colleges; Dr. Susan Polan, representing the American Public Health Association; and Dr. Wile "Chip" Souba, representing the Association of American Medical Colleges.

Dr. Roger Mahr, past president of the American Veterinary Medical Association and a longtime advocate for the "one health" concept, will serve as chief executive officer of the new Commission. "The convergence of human, animal, and environmental health dictates that we embrace the 'one health' concept now," Dr. Mahr said. "We live in a changing environment populated by humans and animals living increasingly interconnected lives. This creates unique health challenges which require integrated solutions and more collaboration across health science professions, academia, government agencies, non-governmental organizations, and industry."

That interconnection between human, animal, and environmental health is playing out in back yards, farms, and health facilities around the world. In addition to the many infectious diseases shared by animals and people, some of the most serious health issues affecting society and driving up healthcare costs -- including obesity, diabetes, and cancer -- are common to pets and people. And, a number of health conditions -- including respiratory ailments -- have a direct link to the quality of our environment.

The Commission's initial action plan calls for hosting a national One Health Summit this fall and conducting a National Academies study on "one health" in 2010. The study will examine the interactions of humans, animals, and the environment in broad terms, which can lead to improvements in human health, animal health, and environmental quality.

The One Health Commission incorporated as a nonprofit organization on June 29, 2009, and held its first Board of Directors meeting on August 14, 2009. Initial funding for the creation of the One Health Commission includes a grant provided by The Rockefeller Foundation.

For more information, visit www. onehealthcommission. org.

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National Youth Leadership Council Supports Senator ColemanÂ’s Federal Youth Coordination Act: Legislation Works to Coordinate and Improve Federal Youth Programs

National Youth Leadership Council Supports Senator ColemanÂ’s Federal Youth Coordination Act: Legislation Works to Coordinate and Improve Federal Youth Programs

(St. Paul) The National Youth Leadership Council™ praises Senator Norm Coleman’s (R-Minn.) introduction of bipartisan legislation to improve coordination of federal programs that assist the nation’s youths. The legislation, the Federal Youth Coordination Act of 2005, was outlined February 16, 2005, at a Capitol Hill news conference. The Act would improve communication among federal agencies serving at-risk youths, assess the needs of this group of young people, set goals for helping them and establish best practices for improving services.

St. Paul, MN (PRWEB) February 20, 2005

The National Youth Leadership Council™ praises Senator Norm Coleman’s (R-Minn.) introduction of bipartisan legislation to improve coordination of federal programs that assist the nation’s youths. The legislation, the Federal Youth Coordination Act of 2005, was outlined February 16, 2005, at a Capitol Hill news conference.

The Act would improve communication among federal agencies serving at-risk youths, assess the needs of this group of young people, set goals for helping them and establish best practices for improving services.

The Act grows out of recommendations from the White House Task Force for Disadvantaged Youth, which found that about 10 million teens in this country are at serious risk of not becoming productive adults. The Task Force also found that programs addressing the problems of these young people are spread across 12 federal departments, with little communication or coordination among them.

“The only thing more complex than the challenges facing young people is the federal government’s effort to support them,” said Dr. James C. Kielsmeier, NYLC’s President and CEO. “This bill will bring efficiency and accountability to federal youth policy. I thank Senator Coleman for his leadership on this legislation.”

In Minnesota, more than 20 percent of high school students will not graduate. Some 43,000 young people, 18-24, are neither in the workforce nor in school. Strategies should be in place to identify youths who are disconnected from their communities, and coordinate educational, vocational and other opportunities so they can reach their potential.

Many of the nationÂ’s youths, especially those already in public systems, have multifaceted needs. In Minnesota, more than 3,100 youths, 15-19, are in the foster care system. National research shows that 55 percent of them will leave the system without a high school diploma, 44 percent will have trouble obtaining health care, and a quarter will be homeless. Supports are in place to meet these needs, but there is little coordination to guide youths through the maze of these systems. The Federal Youth Coordination Act will help to unravel this tangled web.

The legislation would create the Federal Youth Development Council to evaluate, coordinate and improve federal programs serving youths, and hold federal departments accountable for achieving results.

The Council would be charged with additional duties, including:

· Setting quantifiable goals and objectives for federal youth programs, and developing a plan to reach these goals.

· Developing demonstration projects to focus on special populations of youths.

· Conducting research and identifying model programs that can be replicated.

· Supporting state councils which coordinate services for youths.

For more information about the Federal Youth Coordination Act, visit www. youthcoordinationact. org.

About NYLC: NYLC has been at the center of service-leaning program and policy development since 1983. It convenes the annual National Service-Learning Conference, offers adult and youth trainings, and develops service-learning resources. For more information, please visit www. nylc. org.

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Narconon Rehab Doctor Fights Back Against Drug Pushers

Narconon Rehab Doctor Fights Back Against Drug Pushers

A Hyderabad, Pakistan drug rehabilitation doctor is trying to free his poor neighborhood from a damaging, addictive local drug, which he helped get declared illegal. Local drug manufacturers and pushers are threatening the doctor if he doesn't stop this work.

Hyderabad, Pakistan (PRWEB) May 12, 2008

Dr. Muhammad Sharif won't quit. He won't run away. As director of a Narconon drug rehabilitation program operating in a small hospital in the city of Hyderabad, Pakistan, helping the poor and destitute, he expected total public support. And was getting it. But this did not take into account the local drug pushers, whose income his saving of lives from addiction was cutting across. He's been repeatedly and personally threatened recently and is afraid he may have to close his clinic. But that is the last thing he wants to do.

International reports indicate there may be 6 million drug addicts in Pakistan. Being the immediate neighbor of Afghanistan, leading producer of the world's opium, it is no wonder that 50% of Pakistan's drug abusers are addicted to heroin. But this story is not about heroin. The other 50% of illicit drug takers compulsively use cannabis and a regional drug, popular in Pakistan and India, called "main puri." A combination of tobacco mixed with other drugs, main puri is chewed. It is known to cause mouth and throat cancer, oral cavities, and other effects such as a rigidity of the jaw.

Apparently, a manufacturer of main puri works the streets around Dr. Sharif's Narconon program. Until Sharif, the pushers had an open field because main puri, although recognized as addictive and dangerous, had not been officially declared illegal. But Sharif, who has had to deal with its damaging effects, began aggressively giving interviews to the media and issuing press releases. "I strongly protested to the Hyderabad Chief of Police and other community officials," Sharif says. "Partly as a result of this, I am proud to say that 'main puri' has now been banned." Sharif continues. "The main puri manufacturer is threatening me even worse, but I will not surrender in front of them."

Dr. Sharif is an MD, but also recently spent a year studying for his Masters in Public Health degree in Malmo in southern Sweden. The reason he went to study in Malmo was that it was in Sweden that Sharif had earlier completed Narconon drug rehabilitation professional training and internships. While studying for his MPH, he supported himself by working at the Narconon Eslov center near Malmo.

So Sharif knows addicts, in withdrawal, in recovery, and also out on the street. He has been using the Narconon "First Step" program to help street addicts and others come off drugs using vitamins and minerals and hands-on pain relief techniques. The Narconon drug-free, nutrition-assisted approach to drug rehabilitation is based on the research of humanitarian and author L. Ron Hubbard. The Narconon network now comprises over 145 rehabilitation and prevention centers in 45 countries.

It was because of Narconon First Step work that Sharif was invited to bring these methods into a Hyderabad hospital. "We are justly proud of the pioneering work Dr. Sharif has done in Pakistan," says Clark Carr, President Narconon International, who himself has done two lecture tours through the country. "Pakistan is fighting wars on many fronts, and the last thing they can tolerate is rampant drug addiction. Dr. Sharif could help and train other professionals in Pakistan who expressed a wish to open Narconon programs. We hope that the Hyderabad civic community will stand up for the good Dr. Sharif and against the thugs trying to shut down his life-saving work."

Sharif has for some years also been a leading force in Hyderabad for community drug prevention and education. He has lead parades through his and other cities promoting drug prevention and has personally delivered drug education talks to thousands of youth.

He deserves all the support he can get.

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Vivacare Delivers Medication Information to Patients through Doctor Websites

Vivacare Delivers Medication Information to Patients through Doctor Websites

Vivacare provides pharmaceutical and patient support group partners with cost-effective distribution channel for medication information and rebate coupons through its physician network. Vivacare has recently enhanced the educational content to include medication handouts and rebate coupons.

Berkeley, CA (PRWEB) October 13, 2009

Vivacare (http://vivacare. com/) has made it easier for doctors to educate their patients about the medications they prescribe.

Vivacare Inc. provides physicians with the "From Your Doctor (http://fromyourdoctor. com/)" patient education service. Enrolled physicians receive a variety of Web-based patient education tools at no cost, including a Patient Education Library pre-loaded with hundreds of patient handouts written by Vivacare's medical advisors and links to reputable Websites, such as the National Institutes of Health (NIH) and Food and Drug Administration (FDA).

Vivacare has recently enhanced the educational content to include medication handouts and rebate coupons (http://dermatology. fromyourdoctor. com/oregon/portland/portlandderm/health/refills. do). This delivers pharmaceutical information to patients from the source they trust most, their own doctor, leading to improved patient satisfaction and medication adherence.

Vivacare provides healthcare organizations with the opportunity to distribute information about their products or services through it's physician network. Pharmaceutical firms may make their branded, FDA approved content for patients available on the Websites of physicians that prescribe their products. Similarly, patient support groups may make disease state information available in the Patient Education Library of selected medical specialists. This provides Vivacare's partners with a cost-effective alternative to paper-based handouts that often fail to reach their intended audience.

For instance, Gerald Goldberg, M. D. provides his patients with information about the dermatology medications that he prescribes, including Aldara, Differin, Latisse® and Stelara™ (http://dermatology. fromyourdoctor. com/california/berkeley/vivaderm/health/topic. do? title=Stelara+ustekinumab+for+Psoriasis&t=11298). He also provides in-depth information about eczema and rosacea provided by the National Eczema Association and National Rosacea Society in partnership with Vivacare.

"80% of physicians admit to doing a poor job of providing educational content following office visits. Vivacare seeks to help them to deliver the right information to the right patient at the right time", said Mark Becker, M. D., pediatrician and President of Vivacare. "Working with pharmaceutical partners, we help our physicians to educate their patients about the medications that they prescribe. Although many physicians are opposed to direct-to-consumer (DTC) advertising, they appreciate content and programs that help to support their clinical judgment."

The Vivacare service does not allow product advertising on the doctor's Websites and provides physicians the opportunity to control the content to reflect their specialty and personal approach to clinical care.

"Vivacare is an excellent patient education resource tool," says Kate Othus, MHA Administrator of Portland Dermatology Clinic, LLP. "Our Internet savvy patients are directed to our website and if they want more information about their disease - it's all right there. The service saves us hundreds of dollars per month in handout copying and brochure costs while also supporting our efforts to 'go green". Patients have the option to then print any of our handouts themselves, or simply review online."

About Vivacare

Vivacare, based in Berkeley, CA, is a patient education company that helps physicians to educate their patients with the goal of improved clinical care, medication adherence and patient satisfaction. Vivacare has developed services to meet the practice needs of 12 medical specialties, including allergists, cardiologists, dermatologists (http://findadermatologist. com), neurologists, and primary care physicians.

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Birth Arts Doula Training Links up with the Resort Facility, Teleion Holon in Manchester, VT

Birth Arts Doula Training Links up with the Resort Facility, Teleion Holon in Manchester, VT

Birth Arts Doula Training in the fall in the Green Mountains in Vermont. Learn about nature in a nature setting at the retreat center nestled in the mountains.

Springfield, VT (PRWEB) August 17, 2006

Birth Arts offers this weekend-long workshop as part of their doula training program. We meet from 5 pm on Friday until 4 pm on Sunday. There are just some things you cannot get from a book and this is what this workshop provides.

It is designed to be an experiential, hands-on event. In order to get the most out of your workshop time, assignments such as reading and other projects will need to be completed beforehand. We see this as an opportunity to practice what you’ve read about, ask questions of experienced birth assistants, discuss issues and network with other doulas in training. A variety of teaching methods such as extensive role playing, video, discussion and lecture will be used to enhance your learning. Look forward to being a very active participant.

What does Birth Arts Offer that is so special? 

We like to think that Birth Arts is offering students didactic, experiential, and diverse educational experience. We offer students an opportunity to experience education in a deeply personalized and specialized manner. Our educational approach is unique in the doula world and we want to share this with you. When receiving an education from Birth Arts expect to be challenged heart, mind and spirit. We work with students exploring issues that affect birth, affect, education and practice style and hope to train doulas who are comfortable with their role in the doula world.

What does the workshop include? 

Complete doula training. We will cover pregnancy support, labor support techniques, holistic health, anatomy, psychological care in birth and so much more. You will learn what it takes to support all kinds of women. You will also get a chance to explore your beliefs about birth and doula work.

Support techniques, like massage, aromatherapy, flower essences, visualization and so much more are taught to students. Students will also learn about breastfeeding, mother care and birth in various birth settings.

Birth Arts Course Manual– This manual covers all of the class room work. This manual is over 350 pages.

If you have any questions please feel free to contact

Demetria Clark

Phone 866-303-4372

We will have Kara Spencer, author and Birth Arts trainer from the west coast division as a guest teacher.

Location-

The workshop is located at the Teleion Holon Holistic Retreat in Manchester, VT. You can visit the site online at http://arttoscience. org (http://arttoscience. org)

Cost of Workshop - $450.00 This includes lodging, and food and workshop (book and workshop materials). We have managed to work out a great deal for students, in Manchester the average night in a hotel is over $100 a night. Additional family members are $150. for the whole weekend for food and lodging. All meals are organic.

To Register Call 866-303-4372

We accept Check, Money Order, AMEX, Visa, MC and Discover.

To Register by mail send your enrollment fee, name, address, phone and email to

Birth Arts

48 Commonwealth Ave.

Springfield, VT 05156

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Windows 7 64-bit support in latest software release from Big Bang LLC

Windows 7 64-bit support in latest software release from Big Bang LLC

Universal Imaging Utility (UIU) version 4.6 easily creates Windows 7 64-bit hardware-independent image for quick deployment

Milwaukee (PRWEB) June 8, 2010

Today, Big Bang LLC announced the release of the Universal Imaging Utility (UIU) version 4.6 including new upgrades and features for compatibility with Microsoft Windows 7 64-bit. The UIU is patented technology that makes possible the creation of a hardware-independent hard drive image that can easily be deployed to any laptop or desktop regardless of manufacturer. The latest version was developed specifically for compatibility with Windows 7 64-bit.

The new version 4.6 includes features that fully support Windows 7 (32 and 64-bit), a new Windows 7 driver database, support for Mac Intel-based hardware, advanced OS-agnostic UIU Discovery Tool which allows the user to ascertain hardware compatibility for all current Windows Operating Systems, modified Sysprep. xml answer files, enhanced Unsigned driver handling, as well as continued feature updates and support for Windows XP and Vista.

The release of version 4.6 is timely as many organizations have been waiting to upgrade their hardware to coincide with Windows 7 and increasingly more available 64-bit technology. “Many of the existing features of the UIU have been in response to our customers’ needs,” said Big Bang President Adam Murphy, “we try to anticipate market trends and the needs of our customers ahead of time so we can keep their imaging processes as efficient as possible. 64-bit support for Windows 7 is a great example. Most people are only now considering the migration, and we have the newest version all set for them when they are ready to make the move.”

Since 2004, the UIU has enabled IT departments to save considerable time and money. The goal of version 4.6 is to make the creation of a hardware-independent Windows 7 64-bit hard drive image, and subsequent migration to any laptop or desktop regardless of manufacturer considerably more efficient.

The UIU has been effectively deployed to over 2.5 million PCs worldwide in a variety of companies, government and healthcare agencies, and educational institutions.

About Big Bang LLC
Big Bang LLC is a Milwaukee area software developer and training company located in Franklin, WI. In addition to development of the Universal Imaging Utility, they provide training and support for Symantec Ghost Solution Suite. Behind the direction of owner and president Adam Murphy is a customer focused vision. The company seeks to make their unique technology readily available to help IT/Support departments, in the Milwaukee area and around the world, to reduce the time and money typically required for Windows image creation, maintenance, and deployment.

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